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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ntrk1tm1Par
targeted mutation 1, Luis F Parada
MGI:1933963
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ntrk1tm1Par/Ntrk1tm1Par involves: 129S1/Sv * C57BL/6 MGI:2175186
cx2
 		Ntf5tm1Par/Ntf5tm1Par
Ntrk1tm1Par/Ntrk1tm1Par 		involves: 129S1/Sv * C57BL/6 MGI:3613015


Genotype
MGI:2175186
hm1
Allelic
Composition		 Ntrk1tm1Par/Ntrk1tm1Par
Genetic
Background		 involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntrk1tm1Par mutation (0 available); any Ntrk1 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased sensory neuron number ( J:60927 )
• reduction in sensory neuron number by E13
small dorsal root ganglion ( J:60927 )
• 84% reduction of dorsal root ganglion neurons at P0

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
hereditary sensory neuropathy DOID:0050548 OMIM:PS162400
 J:60927




Genotype
MGI:3613015
cx2
Allelic
Composition		 Ntf5tm1Par/Ntf5tm1Par
Ntrk1tm1Par/Ntrk1tm1Par
Genetic
Background		 involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntf5tm1Par mutation (0 available); any Ntf5 mutation (12 available)
Ntrk1tm1Par mutation (0 available); any Ntrk1 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
small dorsal root ganglion ( J:60927 )
• 82% reduction of dorsal root ganglion neurons at P0




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory