Phenotypes associated with this allele

• Allele Symbol: Nkx3-1^tm1Siz
• Allele Name: targeted mutation 1, Seigo Izumo
• Allele ID: MGI:1928655
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nkx3-1^tm1Siz/Nkx3-1^tm1Siz	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	MGI:3027726

Genotype
MGI:3027726

hm1

• Allelic Composition: Nkx3-1^tm1Siz/Nkx3-1^tm1Siz
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal salivary gland morphology ( J:64981 )

abnormal palatine gland morphology ( J:64981 )

decreased ductal branching in the palatine gland ( J:64981 )

increased salivary gland mucosal cell number ( J:64981 )

abnormal prostate gland morphology ( J:64981 )

♂

abnormal prostate gland anterior lobe morphology ( J:64981 )

♂

small prostate gland anterior lobe ( J:64981 )

♂

decreased ductal branching in the coagulating gland ( J:64981 )

♂

prostate gland lateral lobe hypoplasia ( J:64981 )

♂

decreased prostate gland duct number ( J:64981 )

♂

abnormal prostate gland epithelium morphology ( J:64981 )

♂ • prostate epithelial dysplasia

prostate gland epithelial hyperplasia ( J:64981 )

♂

small prostate gland ventral lobe ( J:64981 )

♂

small seminal vesicle ( J:64981 )

♂

reproductive system

abnormal prostate gland morphology ( J:64981 )

♂

abnormal prostate gland anterior lobe morphology ( J:64981 )

♂

small prostate gland anterior lobe ( J:64981 )

♂

decreased ductal branching in the coagulating gland ( J:64981 )

♂

prostate gland lateral lobe hypoplasia ( J:64981 )

♂

decreased prostate gland duct number ( J:64981 )

♂

abnormal prostate gland epithelium morphology ( J:64981 )

♂ • prostate epithelial dysplasia

prostate gland epithelial hyperplasia ( J:64981 )

♂

small prostate gland ventral lobe ( J:64981 )

♂

small seminal vesicle ( J:64981 )

♂

digestive/alimentary system

abnormal salivary gland morphology ( J:64981 )

abnormal palatine gland morphology ( J:64981 )

decreased ductal branching in the palatine gland ( J:64981 )

increased salivary gland mucosal cell number ( J:64981 )