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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Bey
bulgy-eye
MGI:1889298
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Bey/Bey+ 129S/SvEv-Bey MGI:2656223


Genotype
MGI:2656223
ht1
Allelic
Composition
Bey/Bey+
Genetic
Background
129S/SvEv-Bey
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• altered frontal cranial structure is 100% penetrant in males and 75% penetrant in females
• maxillary hypoplasia results in an undershot upper jaw
• upper jaw structures (maxillary bones) are reduced in length
• squat looking face
• abnormalities of the foreface
• nasal bones are reduced in length

skeleton
• altered frontal cranial structure is 100% penetrant in males and 75% penetrant in females
• maxillary hypoplasia results in an undershot upper jaw
• upper jaw structures (maxillary bones) are reduced in length
• nasal bones are reduced in length
• premature closure of the cranial sutures from about 2 weeks after birth, with ossification (synostosis) of the sagittal, metopic, coronal, and interparietal/occipital sutures
• at 9 weeks of age, the sagittal suture is obliterated by ossification, unlike in wild-type controls
• ossification (synostosis) of the intermaxillary suture

vision/eye
• 100% penetrance in males and 75% penetrance in females; bulging eyes are due to skeletal defects as eye size is normal
• increased interorbital distance

growth/size/body
• squat looking face
• abnormalities of the foreface
• nasal bones are reduced in length

respiratory system
• nasal bones are reduced in length

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Crouzon syndrome DOID:2339 OMIM:123500
J:47965





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory