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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Htttm2Mem
targeted mutation 2, Marcy E MacDonald
MGI:1861703
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Htttm2Mem/Htttm2Mem involves: 129S1/Sv * 129X1/SvJ * CD-1 MGI:3698279


Genotype
MGI:3698279
hm1
Allelic
Composition
Htttm2Mem/Htttm2Mem
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Htttm2Mem mutation (2 available); any Htt mutation (36 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• unlike other Hdh alleles that are models for Huntington Disease, homozygotes show no change in striatal mitochondrial sensitivity to calcium in the brain, thus displaying normal striatal and cortical calcium sensitivity

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
NOT Huntington's disease DOID:12858 OMIM:143100
J:99425





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory