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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dync1h1Swl
sprawling
MGI:1861136
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Dync1h1Swl/Dync1h1+ involves: 101/H * C3H/HeH MGI:3844518


Genotype
MGI:3844518
ht1
Allelic
Composition
Dync1h1Swl/Dync1h1+
Genetic
Background
involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dync1h1Swl mutation (3 available); any Dync1h1 mutation (131 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mutants can be unquestionably distinguished from normal siblings at 12 days of age (J:11963)
• when the mouse is lifted the hind limbs flex to the trunk rather than extend as they would for a normal mouse; occasionally the fore limbs will also flex (J:11963)
• during forward motion hind limbs show stiffness on forward motion and move in a wider arc than do hind limbs of normal mice (J:11963)
• hind limbs displace in a rapid vertical direction during locomotion (J:13469)
• during locomotion
• hind limbs are splayed out when mouse is at rest
• by 6 days of age impaired hind limb coordination is obvious

growth/size/body
• for several weeks growth rate is reduced compared to that of normal siblings

reproductive system
• likely due to inability to mate





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory