Phenotypes associated with this allele

• Allele Symbol: Smad2^tm2Enl
• Allele Name: targeted mutation 2, En Li
• Allele ID: MGI:1857693
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Smad2^tm2Enl/Smad2^tm2Enl	involves: 129S4/SvJae	MGI:2182385
ht2	Smad2^tm2Enl/Smad2^+	involves: 129S4/SvJae	MGI:2182386

Genotype
MGI:2182385

hm1

• Allelic Composition: Smad2^tm2Enl/Smad2^tm2Enl
• Genetic Background: involves: 129S4/SvJae

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:48467 )

• phenotype is stated to be identical to that of Smad2^tm1Enl homozygotes; however no data is presented in J:48467

embryo

abnormal rostral-caudal axis patterning ( J:48467 )

embryonic growth retardation ( J:48467 )

growth/size/body

embryonic growth retardation ( J:48467 )

Genotype
MGI:2182386

ht2

• Allelic Composition: Smad2^tm2Enl/Smad2⁺
• Genetic Background: involves: 129S4/SvJae

embryo

embryonic growth retardation ( J:48467 )

abnormal embryonic tissue morphology ( J:48467 )

• phenotype is stated to be identical to that of Smad2^tm1Enl heterozygotes; however no data is presented in J:48467

craniofacial

abnormal craniofacial morphology ( J:48467 )

abnormal mandible morphology ( J:48467 )

growth/size/body

embryonic growth retardation ( J:48467 )

skeleton

abnormal mandible morphology ( J:48467 )

vision/eye

abnormal eye development ( J:48467 )