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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ednrbs-1Chlc
chlorambucil 1Chlc
MGI:1857326
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ednrbs-1Chlc/Ednrbs-1Chlc involves: 101/Rl * C3H/Rl MGI:3777966
ht2
Ednrbs/Ednrbs-1Chlc involves: 101/Rl * C3H/Rl MGI:3777965


Genotype
MGI:3777966
hm1
Allelic
Composition
Ednrbs-1Chlc/Ednrbs-1Chlc
Genetic
Background
involves: 101/Rl * C3H/Rl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrbs-1Chlc mutation (0 available); any Ednrb mutation (103 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• most homozygotes die at 20-38 days of age (J:10322)
• juvenile lethality (J:44601)
• juvenile lethality (J:100221)

digestive/alimentary system

pigmentation
• pigmented areas of fur comprise only ~10% of the surface area (J:10322)
• greater than 90% white spotting (J:100221)

integument
• pigmented areas of fur comprise only ~10% of the surface area (J:10322)
• greater than 90% white spotting (J:100221)




Genotype
MGI:3777965
ht2
Allelic
Composition
Ednrbs/Ednrbs-1Chlc
Genetic
Background
involves: 101/Rl * C3H/Rl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ednrbs mutation (19 available); any Ednrb mutation (103 available)
Ednrbs-1Chlc mutation (0 available); any Ednrb mutation (103 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• similar to Ednrbs homozygotes

integument
• similar to Ednrbs homozygotes





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory