All Phenotypes Gfap<tm1Mes> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gfap^tm1Mes
targeted mutation 1, Albee Messing
MGI:1857176

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gfap^tm1Mes/Gfap^tm1Mes	either: (involves: 129S7/SvEvBrd * 129X1/SvJ) or (involves: 129S7/SvEvBrd * C57BL/6)	MGI:2677145

Allelic Composition	Gfap^tm1Mes/Gfap^tm1Mes
Genetic Background	either: (involves: 129S7/SvEvBrd * 129X1/SvJ) or (involves: 129S7/SvEvBrd * C57BL/6)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gfap^tm1Mes mutation (2 available); any Gfap mutation (47 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal astrocyte morphology ( J:64290 )

enhanced long-term potentiation ( J:64290 )

homeostasis/metabolism

increased susceptibility to injury ( J:48767 )

• mutant mice are highly sensitive to traumatic cervical spinal cord injury, with the presence of subpial and white matter hemorrhages in the ventral and lateral regions of the cervical cord

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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