mortality/aging

• mice die by E16

hematopoietic system

• the number of nucleated fetal erythroblasts is increased compared to controls

abnormal erythropoiesis ( J:25651 )

• erythroid maturation is defective

abnormal erythrocyte morphology ( J:25651 )

• fetal red blood cells are small and irregularly shaped

anemia ( J:25651 )

embryogenesis

• the number of nucleated fetal erythroblasts is increased compared to controls

Mouse Models of Human Disease		OMIM ID	Ref(s)
Beta-Thalassemia		613985	J:25651