Phenotypes associated with this allele

• Allele Symbol: Kitl^Sl-con
• Allele Name: steel contrasted
• Allele ID: MGI:1856163
• Summary: 4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kitl^Sl-con/Kitl^Sl-con	either: (involves: C3H/HeJ) or (involves: C3H/HeN)	MGI:3045115
ht2	Kitl^Sl-con/Kitl^+	either: (involves: C3H/HeJ) or (involves: C3H/HeN)	MGI:3045114
ht3	Kitl^Sl-17H/Kitl^Sl-con	involves: C3H/HeH	MGI:3054452
ht4	Kitl^Sl-18H/Kitl^Sl-con	Not Specified	MGI:3778068

Genotype
MGI:3045115

hm1

• Allelic Composition: Kitl^Sl-con/Kitl^Sl-con
• Genetic Background: either: (involves: C3H/HeJ) or (involves: C3H/HeN)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:23593 )

• uniformly gray coat

abnormal skin pigmentation ( J:23593 )

hyperpigmentation ( J:23593 )

• hyperpigmentation of the genitals

• occasional abnormal pigmentation of regions of the oviduct due to the accumulation of melanocytes

endocrine/exocrine glands

impaired ovarian folliculogenesis ( J:23593 )

♀ • follicular development is initially delayed, and although follicular development is relatively normal around 4 weeks of age, follicles fail to be maintained after 5 weeks of age

hematopoietic system

increased mast cell number ( J:23593 )

• accumulation of mast cells in the reproductive tract, with the highest degree of accumulation in the serosal membrane

immune system

increased mast cell number ( J:23593 )

• accumulation of mast cells in the reproductive tract, with the highest degree of accumulation in the serosal membrane

reproductive system

reproductive system phenotype ( J:23593 )

N • no defects were observed in the postnatal testes

decreased oocyte number ( J:23593 )

♀

impaired ovarian folliculogenesis ( J:23593 )

♀ • follicular development is initially delayed, and although follicular development is relatively normal around 4 weeks of age, follicles fail to be maintained after 5 weeks of age

integument

abnormal coat/hair pigmentation ( J:23593 )

• uniformly gray coat

abnormal skin pigmentation ( J:23593 )

cellular

decreased oocyte number ( J:23593 )

♀

Genotype
MGI:3045114

ht2

• Allelic Composition: Kitl^Sl-con/Kitl⁺
• Genetic Background: either: (involves: C3H/HeJ) or (involves: C3H/HeN)

pigmentation

abnormal skin pigmentation ( J:23593 )

hyperpigmentation ( J:23593 )

• hyperpigmentation of the genital papillae

reproductive system

reproductive system phenotype ( J:23593 )

N • both males and females were fertile

decreased oocyte number ( J:23593 )

♀

abnormal ovarian folliculogenesis ( J:23593 )

♀ • initiation and maintenance of follicles is disrupted

endocrine/exocrine glands

abnormal ovarian folliculogenesis ( J:23593 )

♀ • initiation and maintenance of follicles is disrupted

integument

abnormal skin pigmentation ( J:23593 )

cellular

decreased oocyte number ( J:23593 )

♀

Genotype
MGI:3054452

ht3

• Allelic Composition: Kitl^Sl-17H/Kitl^Sl-con
• Genetic Background: involves: C3H/HeH

pigmentation

diluted coat color ( J:24739 )

• genital papilla remain black

white spotting ( J:24739 )

• on tail and head

integument

diluted coat color ( J:24739 )

• genital papilla remain black

white spotting ( J:24739 )

• on tail and head

Genotype
MGI:3778068

ht4

• Allelic Composition: Kitl^Sl-18H/Kitl^Sl-con
• Genetic Background: Not Specified

pigmentation

diluted coat color ( J:18280 )

• pale grey coat color

head blaze ( J:18280 )

• compound heterozygote displays a prominant white head blaze

integument

diluted coat color ( J:18280 )

• pale grey coat color

head blaze ( J:18280 )

• compound heterozygote displays a prominant white head blaze