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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tyrc-ch
chinchilla
MGI:1855977
Summary 14 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Tyrc-ch/Tyrc-ch involves: C57BL/6 MGI:3794760
ht2
Tyrc-43H/Tyrc-ch involves: 101/H * C3H/HeH MGI:5304168
ht3
Tyrc-ch/Tyrc-ch38H involves: 101/H * C3H/HeH MGI:5304163
ht4
Tyrc-42H/Tyrc-ch involves: 101/H * C3H/HeH MGI:5304166
ht5
Tyrc-112K/Tyrc-ch involves: 101/R1 * C3Hf/R1 * St.2A MGI:3794732
ht6
Tyrc-40H/Tyrc-ch involves: C3H/HeH MGI:5304164
ht7
Tyrc-a/Tyrc-ch involves: C3H/HeJ MGI:4360397
ht8
Tyrcm1OR/Tyrc-ch involves: C3H/Rl MGI:4431055
cx9
Mecp2em1Dkatz/Mecp2em1Dkatz
Tyrc-ch/Tyrc-ch
FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J MGI:6159335
cx10
Mecp2em1Dkatz/Y
Tyrc-ch/Tyrc-ch
FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J MGI:6159336
cx11
Mecp2em1Dkatz/Mecp2+
Tyrc-ch/Tyrc-ch
FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J MGI:6159334
cx12
Tyrc-ch/Del(7)Tyrc-3H involves: 101/H * C3H/HeH MGI:4431256
cx13
Tyrc-ch/Del(7)Tyrc-6H involves: 101/H * C3H/HeH MGI:4843178
cx14
A/A
Tyrc-ch/Tyrc-ch
Not Specified MGI:5460836


Genotype
MGI:3794760
hm1
Allelic
Composition
Tyrc-ch/Tyrc-ch
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice have a grey coat color
• the amount of melanin found in anagen hairbulbs is reduced by more than 30% compared to wild-type mice

integument
• mice have a grey coat color
• the amount of melanin found in anagen hairbulbs is reduced by more than 30% compared to wild-type mice




Genotype
MGI:5304168
ht2
Allelic
Composition
Tyrc-43H/Tyrc-ch
Genetic
Background
involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-43H mutation (0 available); any Tyr mutation (360 available)
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• albino with pink eyes
• albino with pink eyes

vision/eye
• albino with pink eyes

integument
• albino with pink eyes




Genotype
MGI:5304163
ht3
Allelic
Composition
Tyrc-ch/Tyrc-ch38H
Genetic
Background
involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
Tyrc-ch38H mutation (0 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation

integument




Genotype
MGI:5304166
ht4
Allelic
Composition
Tyrc-42H/Tyrc-ch
Genetic
Background
involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-42H mutation (0 available); any Tyr mutation (360 available)
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice resemble Tyrc/Tyrc-ch heterozygotes

integument
• mice resemble Tyrc/Tyrc-ch heterozygotes




Genotype
MGI:3794732
ht5
Allelic
Composition
Tyrc-112K/Tyrc-ch
Genetic
Background
involves: 101/R1 * C3Hf/R1 * St.2A
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-112K mutation (1 available); any Tyr mutation (360 available)
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice have a chinchilla coat color

integument
• mice have a chinchilla coat color




Genotype
MGI:5304164
ht6
Allelic
Composition
Tyrc-40H/Tyrc-ch
Genetic
Background
involves: C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-40H mutation (0 available); any Tyr mutation (360 available)
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice resemble Tyrc/Tyrc-ch heterozygotes

integument
• mice resemble Tyrc/Tyrc-ch heterozygotes




Genotype
MGI:4360397
ht7
Allelic
Composition
Tyrc-a/Tyrc-ch
Genetic
Background
involves: C3H/HeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-a mutation (2 available); any Tyr mutation (360 available)
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• coat color is intermediate between chinchilla and acromelanic homozygotes with a very darkly pigmented anal region

integument
• coat color is intermediate between chinchilla and acromelanic homozygotes with a very darkly pigmented anal region




Genotype
MGI:4431055
ht8
Allelic
Composition
Tyrcm1OR/Tyrc-ch
Genetic
Background
involves: C3H/Rl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
Tyrcm1OR mutation (1 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• areas of white and wild-type agouti fur

integument
• areas of white and wild-type agouti fur




Genotype
MGI:6159335
cx9
Allelic
Composition
Mecp2em1Dkatz/Mecp2em1Dkatz
Tyrc-ch/Tyrc-ch
Genetic
Background
FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2em1Dkatz mutation (0 available); any Mecp2 mutation (37 available)
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system




Genotype
MGI:6159336
cx10
Allelic
Composition
Mecp2em1Dkatz/Y
Tyrc-ch/Tyrc-ch
Genetic
Background
FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2em1Dkatz mutation (0 available); any Mecp2 mutation (37 available)
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• males die by 10 weeks of age




Genotype
MGI:6159334
cx11
Allelic
Composition
Mecp2em1Dkatz/Mecp2+
Tyrc-ch/Tyrc-ch
Genetic
Background
FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2em1Dkatz mutation (0 available); any Mecp2 mutation (37 available)
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• females exhibit a locomotor phenotype onset as early as 14 weeks of age

reproductive system
N
• fertility is normal




Genotype
MGI:4431256
cx12
Allelic
Composition
Tyrc-ch/Del(7)Tyrc-3H
Genetic
Background
involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7)Tyrc-3H mutation (0 available); any Del(7)Tyrc-3H mutation (0 available)
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• the coat color is intermediate between that expected for an albino mouse and a mouse homozygous for chinchilla

integument
• the coat color is intermediate between that expected for an albino mouse and a mouse homozygous for chinchilla




Genotype
MGI:4843178
cx13
Allelic
Composition
Tyrc-ch/Del(7)Tyrc-6H
Genetic
Background
involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7)Tyrc-6H mutation (1 available); any Del(7)Tyrc-6H mutation (0 available)
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• these mice are noticeably lighter in color than mice that are homozygous chinchilla

integument
• these mice are noticeably lighter in color than mice that are homozygous chinchilla




Genotype
MGI:5460836
cx14
Allelic
Composition
A/A
Tyrc-ch/Tyrc-ch
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (19 available); any a mutation (459 available)
Tyrc-ch mutation (78 available); any Tyr mutation (360 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• the contrasted effects of this genotype on eumelanin and phaeomelanin produces a grizzled color pattern or chinchilla effect
• reduced melanin content alters the wild-type agouti color to gray
• in this genotype yellow pigment in the hair shaft is reduced or absent

pigmentation
• reduced melanin content alters the wild-type agouti color to gray
• in this genotype yellow pigment in the hair shaft is reduced or absent





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last database update
09/27/2022
MGI 6.21
The Jackson Laboratory