Gt(ROSA)26Sor^tm1(PF4)Ipek
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1(PF4)Ipek
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Philipp von Hundelshausen
• MGI ID: MGI:7432869
• Synonyms: Cxcl4^tg-L1
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1(PF4)Ipek page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:270132
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The targeting vector introduced into the locus a loxP flanked neomycin and stop cassette, human PF4, and frt-flanked IRES-EGFP. (J:270132)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 944 strains or lines available

References

• Original: J:270132 von Hundelshausen P, et al., Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation. Sci Transl Med. 2017 Apr 05;9(384)
• All: 1 reference(s)