Shc1tm1.1Matz
Targeted Allele Detail
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Symbol: |
Shc1tm1.1Matz |
Name: |
src homology 2 domain-containing transforming protein C1; targeted mutation 1.1, Rachel L Matz |
MGI ID: |
MGI:7424865 |
Synonyms: |
ShcAflox |
Gene: |
Shc1 Location: Chr3:89325858-89337336 bp, + strand Genetic Position: Chr3, 39.11 cM
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Alliance: |
Shc1tm1.1Matz page
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Germline Transmission: |
Earliest citation of germline transmission:
J:217881
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: Ttwo loxP sites flanking exons 2 to 7 and a PKG neomycin resistance cassette flanked by two FRT sites were inserted into the Shc1 locus. Th neomycin resistance cassette was excised by crossing with mice expressing flippase recombinase.
(J:217881)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Shc1 Mutation: |
65 strains or lines available
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Original: |
J:217881 Mlih M, et al., The Src Homology and Collagen A (ShcA) Adaptor Protein Is Required for the Spatial Organization of the Costamere/Z-disk Network during Heart Development. J Biol Chem. 2015 Jan 23;290(4):2419-30 |
All: |
2 reference(s) |
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