Auts2^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Auts2^tm1.1Geno
• Name: autism susceptibility candidate 2; targeted mutation 1.1, Genoway
• MGI ID: MGI:7328748
• Gene: Auts2 Location: Chr5:131466171-132572059 bp, - strand Genetic Position: Chr5, 70.66 cM, cytoband G1
• Alliance: Auts2^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:322808
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct floxed exon 15. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. (J:322808)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Auts2 Mutation: 64 strains or lines available

References

• Original: J:322808 Castanza AS, et al., AUTS2 Regulates RNA Metabolism and Dentate Gyrus Development in Mice. Cereb Cortex. 2021 Aug 26;31(10):4808-4824
• All: 1 reference(s)