Baz2b^em1Hzhu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Baz2b^em1Hzhu
• Name: bromodomain adjacent to zinc finger domain, 2B; endonuclease-mediated mutation 1, Hao Zhu
• MGI ID: MGI:7312211
• Gene: Baz2b Location: Chr2:59729707-60040183 bp, - strand Genetic Position: Chr2, 34.18 cM
• Alliance: Baz2b^em1Hzhu page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 13, within the essential methyl-CpG binding domain. (J:326413)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Baz2b Mutation: 413 strains or lines available

References

• Original: J:326413 Jia Y, et al., In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration. Cell Stem Cell. 2022 Mar 3;29(3):372-385.e8
• All: 1 reference(s)