Letmd1^em1Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Letmd1^em1Mbp
• Name: LETM1 domain containing 1; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:6887450
• Gene: Letmd1 Location: Chr15:100366904-100377045 bp, + strand Genetic Position: Chr15, 56.31 cM
• Alliance: Letmd1^em1Mbp page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 4. (J:321533)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Letmd1 Mutation: 19 strains or lines available

References

• Original: J:321533 Choi KM, et al., Defective brown adipose tissue thermogenesis and impaired glucose metabolism in mice lacking Letmd1. Cell Rep. 2021 Dec 14;37(11):110104
• All: 1 reference(s)