Sox5^tm2.1Tlu
Targeted Allele Detail

Summary

• Symbol: Sox5^tm2.1Tlu
• Name: SRY (sex determining region Y)-box 5; targeted mutation 2.1, Thomas Lufkin
• MGI ID: MGI:6831627
• Synonyms: Sox5^-EGFP+
• Gene: Sox5 Location: Chr6:143774151-144727703 bp, - strand Genetic Position: Chr6, 76.14 cM
• Alliance: Sox5^tm2.1Tlu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:314899
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted an EGFP reporter gene and floxed neomycin resistance cassette at the translation initiation site. Cre-mediated recombination removed the selection cassette. (J:314899)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox5 Mutation: 44 strains or lines available

References

• Original: J:314899 Lee WJ, et al., An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos. Biomed Res Int. 2017;2017:8932583
• All: 1 reference(s)