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Phf19tm1.1Ldc
Targeted Allele Detail
Summary
Symbol: Phf19tm1.1Ldc
Name: PHD finger protein 19; targeted mutation 1.1, Luciano Di Croce
MGI ID: MGI:6827412
Gene: Phf19  Location: Chr2:34783769-34804038 bp, - strand  Genetic Position: Chr2, 23.02 cM, cytoband B
Alliance: Phf19tm1.1Ldc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:313068
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe targeting construct inserted a loxP site upstream of exon 4 and a neomycin resistance cassette with 3' loxP site downstream of exon 5. Cre-mediated recombination removed exons 4 and 5 as well as the selection cassette. (J:313068)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Phf19 Mutation:  26 strains or lines available
References
Original:  J:313068 Vizan P, et al., The Polycomb-associated factor PHF19 controls hematopoietic stem cell state and differentiation. Sci Adv. 2020 Aug;6(32):eabb2745
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory