Cfap53^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cfap53^em1Cya
• Name: cilia and flagella associated protein 53; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6724260
• Synonyms: Cfap53^em1Cgen
• Gene: Cfap53 Location: Chr18:74416171-74493055 bp, + strand Genetic Position: Chr18, 50.7 cM, cytoband E2
• Alliance: Cfap53^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed exons 4 through 6. (J:307591)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cfap53 Mutation: 56 strains or lines available

References

• Original: J:307591 Wu B, et al., Essential Role of CFAP53 in Sperm Flagellum Biogenesis. Front Cell Dev Biol. 2021;9:676910
• All: 1 reference(s)