Tchp^tm1Inag
Targeted Allele Detail

Summary

• Symbol: Tchp^tm1Inag
• Name: trichoplein, keratin filament binding; targeted mutation 1, Masaki Inagaki
• MGI ID: MGI:6711105
• Gene: Tchp Location: Chr5:114845821-114860388 bp, + strand Genetic Position: Chr5, 55.99 cM, cytoband F
• Alliance: Tchp^tm1Inag page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:304307
• Parent Cell Line: EB3 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• An EN2intron1-2EN2SA IRES beta-geo cassette replaced exon 2-8. (J:304307)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tchp Mutation: 21 strains or lines available

References

• Original: J:304307 Yamakawa D, et al., Primary cilia-dependent lipid raft/caveolin dynamics regulate adipogenesis. Cell Rep. 2021 Mar 9;34(10):108817
• All: 1 reference(s)