Mirc34^em1Jnch
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mirc34^em1Jnch
• Name: microRNA cluster 34, including Mir449a through Mir449c; endonuclease-mediated mutation 1, Jun-An Chen
• MGI ID: MGI:6696374
• Synonyms: Mir449^-
• Gene: Mirc34 Location: Chr13:113172517-113174158 bp Genetic Position: Chr13, Syntenic

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mirc34^em1Jnch involves 4 genes/genome features (Cdc20b, Mir449c, Mir449b ...) View all
• CRISPR targeting deleted 1.76 kb, which includes all three 449 microRNAs. (J:304721)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc34 Mutation: 1 strain or line available

References

• Original: J:304721 Chang SH, et al., MicroRNAs mediate precise control of spinal interneuron populations to exert delicate sensory-to-motor outputs. Elife. 2021 Mar 31;10:e63768
• All: 2 reference(s)