About   Help   FAQ
Fam3dem1Wko
Endonuclease-mediated Allele Detail
Summary
Symbol: Fam3dem1Wko
Name: FAM3 metabolism regulating signaling molecule D; endonuclease-mediated mutation 1, Wei Kong
MGI ID: MGI:6695714
Gene: Fam3d  Location: Chr14:14091019-14120836 bp, + strand  Genetic Position: Chr14, 4.83 cM, cytoband A1
Alliance: Fam3dem1Wko page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsTALEN-mediated gene targeting deleted one cytosine base in exon 3. Western blot analysis confirmed the absence of protein in colon, heart, and spleen. (J:304594)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fam3d Mutation:  13 strains or lines available
References
Original:  J:304594 He L, et al., Deficiency of FAM3D (Family With Sequence Similarity 3, Member D), A Novel Chemokine, Attenuates Neutrophil Recruitment and Ameliorates Abdominal Aortic Aneurysm Development. Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1616-1631
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory