Colgalt1tm1.1Gpt
Targeted Allele Detail
|
Symbol: |
Colgalt1tm1.1Gpt |
Name: |
collagen beta(1-O)galactosyltransferase 1; targeted mutation 1, GemPharmatech, Co., Ltd |
MGI ID: |
MGI:6694288 |
Gene: |
Colgalt1 Location: Chr8:72063642-72077555 bp, + strand Genetic Position: Chr8, 34.43 cM
|
Alliance: |
Colgalt1tm1.1Gpt page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:283330
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
Not Specified
|
|
Allele Type: |
|
Targeted (Null/knockout) |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and second loxP site were inserted downstream of exon 3 via homologous recombination. Cre mediated recombination removed exons 2 and 3 and the neo cassette. Western blot analysis confirmed the absence of protein expression in homozygous embryos at E10.5.
(J:283330)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Colgalt1 Mutation: |
25 strains or lines available
|
|
Original: |
J:283330 He L, et al., Down-regulation of GLT25D1 inhibited collagen secretion and involved in liver fibrogenesis. Gene. 2020 Mar 1;729:144233 |
All: |
1 reference(s) |
|