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Fitm1tm1Nani
Targeted Allele Detail
Summary
Symbol: Fitm1tm1Nani
Name: fat storage-inducing transmembrane protein 1; targeted mutation 1, Natsumi Nishihama
MGI ID: MGI:6690472
Synonyms: Fitm1-
Gene: Fitm1  Location: Chr14:55813131-55814409 bp, + strand  Genetic Position: Chr14, 28.19 cM
Alliance: Fitm1tm1Nani page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:303195
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion, Intragenic deletion
    The entire 2-exon gene was replaced with a neomycin resistance gene cassette. (J:303195)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fitm1 Mutation:  12 strains or lines available
References
Original:  J:303195 Nishihama N, et al., Mice lacking fat storage-inducing transmembrane protein 2 show improved profiles upon pressure overload-induced heart failure. Heliyon. 2019 Mar;5(3):e01292
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory