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Prps1l1em1Wyan
Endonuclease-mediated Allele Detail
Summary
Symbol: Prps1l1em1Wyan
Name: phosphoribosyl pyrophosphate synthetase 1-like 1; endonuclease-mediated mutation 1, Wei Yan
MGI ID: MGI:6509043
Gene: Prps1l1  Location: Chr12:35034760-35036435 bp, + strand  Genetic Position: Chr12, 15.64 cM, cytoband B2
Alliance: Prps1l1em1Wyan page
Mutation
origin
Strain of Origin:  (FVB/NJ x C57BL/6J)F1
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR/Cas9 technology deleted approximately 1 kb of the coding sequence and generated a knock-out allele. qPCR confirmed absence of mRNA in the testes. (J:301638)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prps1l1 Mutation:  15 strains or lines available
References
Original:  J:301638 Wang Z, et al., Prps1l1, a testis-specific gene, is dispensable for mouse spermatogenesis. Mol Reprod Dev. 2018 Oct;85(10):802-804
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory