About   Help   FAQ
Spg21tm1Mchan
Targeted Allele Detail
Nomenclature
Symbol: Spg21tm1Mchan
Name: SPG21, maspardin; targeted mutation 1, Michael C Hanna
MGI ID: MGI:6508399
Gene: Spg21  Location: Chr9:65368229-65395752 bp, + strand  Genetic Position: Chr9, 35.32 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:302256
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe luciferase gene and a loxP-flanked neomcycin resistance gene replaced exon 3. Western blot analysis confirmed absence of protein. (J:302256)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spg21 Mutation:  19 strains or lines available
References
Original:  J:302256 Soderblom C, et al., Targeted disruption of the Mast syndrome gene SPG21 in mice impairs hind limb function and alters axon branching in cultured cortical neurons. Neurogenetics. 2010 Oct;11(4):369-78
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/03/2022
MGI 6.21
The Jackson Laboratory