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Tuba4am1Frla
Chemically induced Allele Detail
Summary
Symbol: Tuba4am1Frla
Name: tubulin, alpha 4A; mutation 1, Francois Lanza
MGI ID: MGI:6441799
Synonyms: Tuba4aPlt68, Tuba4aV260E
Gene: Tuba4a  Location: Chr1:75190872-75196509 bp, - strand  Genetic Position: Chr1, 38.63 cM, cytoband C3
Alliance: Tuba4am1Frla page
Mutation
origin
Strain of Origin:  BALB/c
Mutation
description
Allele Type:    Chemically induced (ENU) (Hypomorph)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis created a T-to-A mutation that results in the substitution of valine codon 260 with glutamic acid (p.V260E). (J:286522)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tuba4a Mutation:  30 strains or lines available
References
Original:  J:286522 Strassel C, et al., An essential role for alpha4A-tubulin in platelet biogenesis. Life Sci Alliance. 2019 Feb;2(1)
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory