Gpr35^em1Niess
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gpr35^em1Niess
• Name: G protein-coupled receptor 35; endonuclease-mediated mutation 1, Jan Hendrik Niess
• MGI ID: MGI:6436880
• Gene: Gpr35 Location: Chr1:92878587-92914113 bp, + strand Genetic Position: Chr1, 46.65 cM, cytoband D
• Alliance: Gpr35^em1Niess page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed exon 2 and the 3' UTR. (J:300275)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr35 Mutation: 32 strains or lines available

References

• Original: J:300275 Kaya B, et al., Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1(+) Macrophages Regulates Intestinal Homeostasis. Cell Rep. 2020 Aug 4;32(5):107979
• All: 1 reference(s)