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Endonuclease-mediated Allele Detail
Symbol: Adnpem1Ant
Name: activity-dependent neuroprotective protein; endonuclease-mediated mutation 1, Frank Kooy
MGI ID: MGI:6416397
Gene: Adnp  Location: Chr2:168180986-168207112 bp, - strand  Genetic Position: Chr2, 88.41 cM
Strain of Origin:  C57BL/6NJcl
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsCRISPR/Cas9 genome editing introduced a 14 nucleotide deletion such that Leucine822 is replaced by Histidine and followed by 6 amino acids and a termination codon in exon 5. The deletion causes a frameshift and is predicted to result in a truncated protein.
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adnp Mutation:  55 strains or lines available
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
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