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Tg(Ace2-ACE2)1Cqin
Transgene Detail
Nomenclature
Symbol: Tg(Ace2-ACE2)1Cqin
Name: transgene insertion 1, Chuan Qin
MGI ID: MGI:6401292
Synonyms: hACE2
Transgene: Tg(Ace2-ACE2)1Cqin  Location: unknown  
Transgene
origin
Strain of Origin:  ICR
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Ace2-ACE2)1Cqin expresses 1 gene
 
Mutation detailsHuman ACE2 (hACE2) cDNA upstream of the SV40 poly A tract was placed under the regulatory control of mouse Ace2 promoter sequences (9 kb) derived from BAC RP23-75P20. (J:141460)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:141460 Yang XH, et al., Mice transgenic for human angiotensin-converting enzyme 2 provide a model for SARS coronavirus infection. Comp Med. 2007 Oct;57(5):450-9
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory