Tg(PODXL-rtTA*M2)#Mjmr
Transgene Detail

Summary

• Symbol: Tg(PODXL-rtTA*M2)#Mjmr
• Name: transgene insertion, Marcus J Moeller
• MGI ID: MGI:6400996
• Synonyms: PEC-rtTA
• Transgene: Tg(PODXL-rtTA*M2)#Mjmr Location: unknown
• Alliance: Tg(PODXL-rtTA*M2)#Mjmr page

Transgene origin

• Strain of Origin: 129S/Sv x C57BL/6J

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: Three kb of the human podocalyxin (PODXL1) 5' flanking region drives parietal epithelial cell-spcific exression of an optimized form of the reverse tetracycline-controlled transactivator (rtTA*M2) protein. Four lines were created. The pound symbol (#) is used when no lines are specified and/or lines are pooled. (J:285836)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:285836 Appel D, et al., Recruitment of podocytes from glomerular parietal epithelial cells. J Am Soc Nephrol. 2009;20(2):333-43
• All: 6 reference(s)