About   Help   FAQ
Garsem2Rwb
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Garsem2Rwb
Name: glycyl-tRNA synthetase; endonuclease-mediated mutation 2, Robert W Burgess
MGI ID: MGI:6393282
Synonyms: GarsdeltaETAQ
Gene: Gars  Location: Chr6:55038007-55079500 bp, + strand  Genetic Position: Chr6, 27.29 cM
Mutation
origin
Strain of Origin:  (FVB/NJ x C57BL/6NJ)F1
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Intragenic deletion
    CRISPR/Cas9 technology generated a 12 bp deletion (bases 12-23) in exon 8. (J:284948)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gars Mutation:  29 strains or lines available
References
Original:  J:284948 Morelli KH, et al., Allele-specific RNA interference prevents neuropathy in Charcot-Marie-Tooth disease type 2D mouse models. J Clin Invest. 2019 Dec 2;129(12):5568-5583
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/23/2021
MGI 6.16
The Jackson Laboratory