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Targeted Allele Detail
Symbol: Arf4tm1Tsdk
Name: ADP-ribosylation factor 4; targeted mutation 1, Tetsushi Sadakata
MGI ID: MGI:6368994
Synonyms: Arf4(loxP)
Gene: Arf4  Location: Chr14:26359289-26377997 bp, + strand  Genetic Position: Chr14, 16.09 cM
Germline Transmission:  Earliest citation of germline transmission: J:279779
Parent Cell Line:  B6-3i/HK3i (ES Cell)
Strain of Origin:  C57BL/6NJcl
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsAn FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 3. (J:279779)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arf4 Mutation:  18 strains or lines available
Original:  J:279779 Hosoi N, et al., Deletion of Class II ADP-Ribosylation Factors in Mice Causes Tremor by the Nav1.6 Loss in Cerebellar Purkinje Cell Axon Initial Segments. J Neurosci. 2019 Aug 7;39(32):6339-6353
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.21
The Jackson Laboratory