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Phldb2tm1Msat
Targeted Allele Detail
Summary
Symbol: Phldb2tm1Msat
Name: pleckstrin homology like domain, family B, member 2; targeted mutation 1, Makoto Sato
MGI ID: MGI:6364613
Synonyms: Phldb2exon2-neo
Gene: Phldb2  Location: Chr16:45566606-45773961 bp, - strand  Genetic Position: Chr16, 30.08 cM
Alliance: Phldb2tm1Msat page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:275597
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout)
Mutation:    Insertion
    Exon 2 was replaced by a floxed exon 2 and neomycin resistance cassette. (J:275597)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Phldb2 Mutation:  66 strains or lines available
References
Original:  J:275597 Xie MJ, et al., PIP3-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover. Sci Rep. 2019 Mar 13;9(1):4305
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory