Tmprss11b^em2Bug
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmprss11b^em2Bug
• Name: transmembrane protease, serine 11B; endonuclease-mediated mutation 2, Thomas H Bugge
• MGI ID: MGI:6364132
• Gene: Tmprss11b Location: Chr5:86806326-86824221 bp, - strand Genetic Position: Chr5, 43.56 cM
• Alliance: Tmprss11b^em2Bug page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 2 bp (c.14_15delTC; V5fsX52). (J:279596)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmprss11b Mutation: 25 strains or lines available

References

• Original: J:279596 Callies LK, et al., Iterative, multiplexed CRISPR-mediated gene editing for functional analysis of complex protease gene clusters. J Biol Chem. 2019 Sep 9
• All: 1 reference(s)