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Orm1tm1Smoc
Targeted Allele Detail
Summary
Symbol: Orm1tm1Smoc
Name: orosomucoid 1; targeted mutation 1, Shanghai Model Organisms Center
MGI ID: MGI:6357675
Gene: Orm1  Location: Chr4:63262797-63266400 bp, + strand  Genetic Position: Chr4, 33.96 cM
Alliance: Orm1tm1Smoc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:264446
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1-5 were replaced with an frt-flanked neomycin selection cassette. Western blots of protein extracts from liver and muscle tissues derived from homozygous mutant mice demonstrated the absence of the encoded protein. (J:264446)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Orm1 Mutation:  13 strains or lines available
References
Original:  J:264446 Lei H, et al., Fatigue-induced Orosomucoid 1 Acts on C-C Chemokine Receptor Type 5 to Enhance Muscle Endurance. Sci Rep. 2016 Jan 7;6:18839
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory