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Plekhn1tm1Hkon
Targeted Allele Detail
Nomenclature
Symbol: Plekhn1tm1Hkon
Name: pleckstrin homology domain containing, family N member 1; targeted mutatino 1, Hiroaki Konishi
MGI ID: MGI:6356362
Synonyms: CLPABP floxed
Gene: Plekhn1  Location: Chr4:156305913-156312999 bp, - strand  Genetic Position: Chr4, 88.63 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:251603
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
    Exons 3-8 were flanked with loxP sites and an frt-flanked neomycin selection cassette. (J:251603)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Plekhn1 Mutation:  32 strains or lines available
References
Original:  J:251603 Nishino T, et al., Antagonizing effect of CLPABP on the function of HuR as a regulator of ARE-containing leptin mRNA stability and the effect of its depletion on obesity in old male mouse. Biochim Biophys Acta. 2016 Nov;1861(11):1816-1827
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/27/2022
MGI 6.21
The Jackson Laboratory