Camsap2^tm1Ltm
Targeted Allele Detail

Summary

• Symbol: Camsap2^tm1Ltm
• Name: calmodulin regulated spectrin-associated protein family, member 2; targeted mutation 1, Masatoshi Takeichi
• MGI ID: MGI:6355951
• Synonyms: Camsap2^-
• Gene: Camsap2 Location: Chr1:136195861-136273842 bp, - strand Genetic Position: Chr1, 59.61 cM
• Alliance: Camsap2^tm1Ltm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:265916
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A loxP flanked neo selection cassette was inserted into the 5th exon. Western blot analysis confirmed the absence of protein expression in homozygous mutant mice. (J:265916)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Camsap2 Mutation: 65 strains or lines available

References

• Original: J:265916 Pongrakhananon V, et al., CAMSAP3 maintains neuronal polarity through regulation of microtubule stability. Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):9750-9755
• All: 1 reference(s)