Atm^m6Btlr
Chemically induced Allele Detail

Summary

• Symbol: Atm^m6Btlr
• Name: ataxia telangiectasia mutated; mutation 6, Bruce Beutler
• MGI ID: MGI:6305816
• Synonyms: antebellum
• Gene: Atm Location: Chr9:53350449-53448040 bp, - strand Genetic Position: Chr9, 29.12 cM, cytoband C-D
• Alliance: Atm^m6Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: C to T substitution at base pair 53,518,559 (v38) on chromosome 9, or base pair 18,258 in the GenBank genomic regionNC_000075.The mutation corresponds to a G>A substitution at residue 1,315 in the mRNA sequence NM_007499 within exon 9 of 64 total exons. The mutation results in substitution of tryptophan 392 for a premature stop codon (W392*) in the ATM protein. (J:274964)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atm Mutation: 169 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4418

References

• Original: J:274964 Choi JH, et al., Mutagenetix entry for antebellum. MGI Direct Data Submission. 2019
• All: 1 reference(s)