Kit^W-3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Kit^W-3Btlr
• Name: KIT proto-oncogene receptor tyrosine kinase; viable dominant spotting 3 Bruce Beutler
• MGI ID: MGI:6304941
• Synonyms: mooyah2
• Gene: Kit Location: Chr5:75735647-75817382 bp, + strand Genetic Position: Chr5, 39.55 cM
• Alliance: Kit^W-3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 75,652,808 (v38) on chromosome 5, or base pair 77,822 in the GenBank genomic region NC_000071.6 encoding Kit. The mutation corresponds to residue 2,703 in the mRNA sequence NM_021099.3 within exon 19 of 21 total exons. The mutation results in an isoleucine to asparagine substitution at position 881 (I881N) in the KIT protein. (J:274823)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kit Mutation: 179 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4209

References

• Original: J:274823 Arnold A, et al., Mutagenetix entry for mooyah2. MGI Direct Data Submission. 2019
• All: 1 reference(s)