Rasgrp1^m5Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rasgrp1^m5Btlr
• Name: RAS guanyl releasing protein 1; mutation 5, Bruce Beutler
• MGI ID: MGI:6286073
• Synonyms: sea_bass
• Gene: Rasgrp1 Location: Chr2:117110464-117173358 bp, - strand Genetic Position: Chr2, 59.19 cM
• Alliance: Rasgrp1^m5Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 117,282,654 (v38) on chromosome 2, or base pair 60,224 in the GenBank genomic region NC_000068 encoding Rasgrp1. The mutation corresponds to residue 2,444 in the mRNA sequence NM_011246 within exon 17 of 17 total exons. The mutation results in an aspartic acid to glycine substitution at position 759 (D759G) in the RasGRP1 protein. (J:272846)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rasgrp1 Mutation: 55 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3825

References

• Original: J:272846 Zhong X, et al., Mutagenetix entry for sea_bass. MGI Direct Data Submission. 2019
• All: 1 reference(s)