Prkdc^m13Btlr
Chemically induced Allele Detail

Summary

• Symbol: Prkdc^m13Btlr
• Name: protein kinase, DNA activated, catalytic polypeptide; mutation 13, Bruce Beutler
• MGI ID: MGI:6285188
• Synonyms: elmer_fudd
• Gene: Prkdc Location: Chr16:15455730-15660099 bp, + strand Genetic Position: Chr16, 10.09 cM, cytoband B1
• Alliance: Prkdc^m13Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 15,808,058 (v38) on chromosome 16, or base pair 170,616 in the GenBank genomic region NC_000082 for Prkdc. The mutation corresponds to residue 9,970 in the mRNA sequence NM_011159 within exon 71 of 86 total exons. The mutation results in a leucine to serine substitution at position 3,316 (L3316S) in the DNA-PKCS protein. (J:272441)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkdc Mutation: 408 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3811

References

• Original: J:272441 Zhong X, et al., Mutagenetix entry for elmer_fudd. MGI Direct Data Submission. 2019
• All: 1 reference(s)