Clcnka^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Clcnka^m1Btlr
• Name: chloride channel, voltage-sensitive Ka; mutation 1, Bruce Beutler
• MGI ID: MGI:6283545
• Synonyms: free_trade
• Gene: Clcnka Location: Chr4:141111922-141126017 bp, - strand Genetic Position: Chr4, 73.94 cM
• Alliance: Clcnka^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Translocation
• Mutation details: ENU-induced T to A transversion at base pair 141,395,158 (v38) on chromosome 4, or base pair 3,549 in the GenBank genomic region NC_000070 encoding Clcnka. The mutation corresponds to residue 592 in the mRNA sequence NM_024412 within exon 6 of 20 total exons. The mutation results in substitution of tyrosine 179 for a premature stop codon (Y179*). (J:271974)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clcnka Mutation: 21 strains or lines available

Notes

https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=2743

References

• Original: J:271974 Turer E, et al., Mutagenetix entry for free_trade. MGI Direct Data Submission. 2019
• All: 1 reference(s)