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Kdm6btm1.1Masn
Targeted Allele Detail
Nomenclature
Symbol: Kdm6btm1.1Masn
Name: KDM1 lysine (K)-specific demethylase 6B; targeted mutation 1.1, Masahide Asano
MGI ID: MGI:6277129
Synonyms: Jmjd3delta18
Gene: Kdm6b  Location: Chr11:69289334-69304501 bp, - strand  Genetic Position: Chr11, 42.6 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:247259
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 18 was replaced by a loxP flanked exon 18 and FRT-flanked neomycin resistance gene via homologous recombination. Cre-mediated recombination deleted exon 18, leaving the neomycin gene. (J:247259)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Kdm6b Mutation:  51 strains or lines available
References
Original:  J:247259 Naruse C, et al., New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice. FASEB J. 2017 Jun;31(6):2252-2266
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory