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Acsl6tm1.1Jeme
Targeted Allele Detail
Nomenclature
Symbol: Acsl6tm1.1Jeme
Name: acyl-CoA synthetase long-chain family member 6; targeted mutation 1.1, Jessica M Ellis
MGI ID: MGI:6268795
Synonyms: Acsl6-
Gene: Acsl6  Location: Chr11:54303805-54364756 bp, + strand  Genetic Position: Chr11, 32.13 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:267563
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsLoxP sites were inserted into introns 1 and 2. Subsequent cre-mediated recombination deleted exon 2, creating a knockout allele. Western blots confirmed the absence of protein expression from the locus. (J:267563)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Acsl6 Mutation:  1 strain or line available
References
Original:  J:267563 Fernandez RF, et al., Acyl-CoA synthetase 6 enriches the neuroprotective omega-3 fatty acid DHA in the brain. Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):12525-12530
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory