Cdh23^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Cdh23^m2Btlr
• Name: cadherin related 23 (otocadherin); mutation 2, Bruce Beutler
• MGI ID: MGI:6268401
• Synonyms: hersey
• Gene: Cdh23 Location: Chr10:60138527-60532269 bp, - strand Genetic Position: Chr10, 30.11 cM
• Alliance: Cdh23^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 60,308,036 (v38) on chromosome 10, or base pair 388,478 in the GenBank genomic region NC_000076.6. The mutation corresponds to residue 9,196 in the mRNA sequence NM_023370.3 within exon 61 of 70 total exons. The mutation results in a valine to glutamic acid substitution at position 2,928 (V2928E) in the Cdh23 protein. (J:267489)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdh23 Mutation: 280 strains or lines available

References

• Original: J:267489 Prince L, et al., Mutagenetix entry for hersey. MGI Direct Data Submission. 2018
• All: 1 reference(s)