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Nntem1(IMPC)H
Endonuclease-mediated Allele Detail
Summary
Symbol: Nntem1(IMPC)H
Name: nicotinamide nucleotide transhydrogenase; endonuclease-mediated mutation 1, Harwell
MGI ID: MGI:6257492
Gene: Nnt  Location: Chr13:119472063-119545793 bp, - strand  Genetic Position: Chr13, 67.21 cM, cytoband D2
Alliance: Nntem1(IMPC)H page
IMPC: Nnt gene page
Mutation
origin
Strain of Origin:  C57BL/6NTac
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 RNA, 4 guide sequences CTTGTCAAAAACAGCAGTCTGGG, CCTTGTCAAAAACAGCAGTCTGG, GAGCATGGCCGAGATTACTCCGG, ATGCTTGGCCGGAGTAATCTCGG, and a non-contributing oligo, which resulted in a Exon Deletion. (J:265051)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Nnt Mutation:  63 strains or lines available
References
Original:  J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory