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Clasp2em1Adiuj
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Clasp2em1Adiuj
Name: CLIP associating protein 2; endonuclease-mediated mutation 1, MODEL-AD Center
MGI ID: MGI:6202928
Gene: Clasp2  Location: Chr9:113741473-113919682 bp, + strand  Genetic Position: Chr9, 64.06 cM, cytoband F2
Mutation
origin
Strain of Origin:  B6(SJL)-Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/J
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Nucleotide substitutions
 
Mutation detailsA plasmids encoding a single guide RNA designed to introduce the L163P point mutation (CTG to CCA) into the gene and the cas9 nuclease were introduced into the cytoplasm of fertilized eggs with well recognized pronuclei. (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Clasp2 Mutation:  2 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/21/2020
MGI 6.14
The Jackson Laboratory