Slc30a2^tm1Kgna
Targeted Allele Detail

Summary

• Symbol: Slc30a2^tm1Kgna
• Name: solute carrier family 30 (zinc transporter), member 2; targeted mutation 1, Keigo Nishida
• MGI ID: MGI:6202882
• Synonyms: Slc30a2^tm1Thir
• Gene: Slc30a2 Location: Chr4:134070492-134081795 bp, + strand Genetic Position: Chr4, 66.61 cM
• Alliance: Slc30a2^tm1Kgna page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:264481
• Parent Cell Line: M1/M-1 (ES Cell)
• Strain of Origin: (129 x C57BL/6)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced exons 5 and 6. (J:264481)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc30a2 Mutation: 28 strains or lines available

References

• Original: J:264481 Lee S, et al., Essential Role for Zinc Transporter 2 (ZnT2)-mediated Zinc Transport in Mammary Gland Development and Function during Lactation. J Biol Chem. 2015 May 22;290(21):13064-78
• All: 5 reference(s)