Atm^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Atm^m1Btlr
• Name: ataxia telangiectasia mutated; mutation 1, Bruce Beutler
• MGI ID: MGI:6200331
• Synonyms: mockingbird
• Gene: Atm Location: Chr9:53350449-53448040 bp, - strand Genetic Position: Chr9, 29.12 cM, cytoband C-D
• Alliance: Atm^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to T transversion at base pair 53,516,467 (v38) on chromosome 9, or base pair 20,350 in the GenBank genomic region NC_000075 encoding Atm. The mutation corresponds to residue 1,481 in the mRNA sequence NM_007499 within exon 10 of 64 total exons. The mutation results in substitution of glycine 448 for a premature stop codon (G448*) in the ATM protein. (J:265252)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atm Mutation: 169 strains or lines available

References

• Original: J:265252 Zhong X, et al., Mutagenetix entry for mockingbird. MGI Direct Data Submission. 2018
• All: 1 reference(s)